Molecular Characteristics
Complete Specifications
Structural Composition
Modified 37-amino-acid human amylin analog with residue substitutions and fatty-acid acylation
Physical Properties
Cagrilintide is a synthetic 37-amino-acid peptide engineered as a long-acting amylin analog. Structural modifications, including targeted amino acid substitutions and lipidation (acylation), enhance molecular stability and extend structural persistence under controlled research conditions. The presence of disulfide linkages contributes to conformational stability, while lyophilized formulation supports extended shelf stability when protected from light, moisture, and repeated freeze–thaw cycles. Proper cold storage preserves peptide integrity for laboratory and analytical applications.
Analysis & Documentation
Identity
Each production lot is checked against the reference structure recorded for this compound:
- Classification — Synthetic acylated 37-residue amylin analog
- Molecular formula — C₁₉₄H₃₁₂N₅₄O₅₉S₂
- Expected mass — ~4,409 Da
- CAS registry — 1415456-99-3
- Chain length — 37 amino acids (modified)
- PubChem CID — Not available
Analytical Methods
Testing is carried out per lot by an independent laboratory. The methods measure what the material is and how much of it is the target compound:
- RP-HPLC — reverse-phase separation of the target from process-related impurities; purity is reported as area percent of the main peak
- Mass spectrometry — observed mass compared against the expected molecular mass above
- Retention time — compared against a reference standard run under the same conditions
- Chromatogram — reproduced on the certificate so the peak and any shoulders can be inspected directly
Material & Documentation
What arrives, and how to tie it back to its paperwork:
- Appearance as supplied — White to off-white lyophilized powder
- Solubility — Water, phosphate-buffered saline (PBS)
- Lot number — printed on the container label and used to look up the certificate
- Certificate — indexed by lot at Certificates of Analysis
Laboratory Handling and Storage Protocols
Lyophilized Powder Storage
- Store at –20°C to –80°C in the original, sealed vial
- Protect from light exposure and moisture
- A desiccated storage environment is recommended
- Stability data suggests extended stability when stored at −20 °C or below.
Stability Characteristics
Cagrilintide is a synthetic peptide research compound that demonstrates good stability under controlled laboratory conditions. Maintaining appropriate cold storage of the lyophilized material, minimizing mechanical agitation during reconstitution, and limiting freeze–thaw exposure help preserve structural integrity and solubility. When handled according to standard peptide protocols, Cagrilintide supports consistent use in in vitro and analytical research applications.
Frequently Asked Questions
What is Cagrilintide?
Cagrilintide is a synthetic acylated 37-residue analogue of human amylin. It is supplied as a lyophilized powder for laboratory use, with identity and purity reported per lot on the Certificate of Analysis.
How does Cagrilintide differ from native amylin?
Cagrilintide differs from native human amylin by targeted residue substitutions and by acylation with a fatty-acid side chain. Those modifications change its molecular formula and mass, both of which are recorded above and confirmed per lot.
How is Cagrilintide supplied?
Cagrilintide is supplied as a lyophilized (freeze-dried) powder in a sealed vial, a form chosen for stability during storage and transport.
How should lyophilized Cagrilintide be stored?
Lyophilized Cagrilintide should be stored:
-
Long-term: −20 °C to −80 °C
-
Short-term: 2–8 °C
Vials should remain sealed and protected from light and moisture.
Is Cagrilintide FDA-approved?
No. Cagrilintide is not an FDA-approved drug. This product is sold as a research chemical for laboratory use only and must not be marketed or used for diagnostic, therapeutic, or consumption purposes.
Does Cagrilintide require a Certificate of Analysis (COA)?
Yes. A Certificate of Analysis (COA) should be available for each batch of Cagrilintide, verifying identity, purity, and analytical testing results to ensure research quality and traceability.
This product is not for human consumption. It is sold strictly for research and educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.
Any clinical data or research information referenced on this page is derived from peer-reviewed scientific literature and official publications. This information is provided for educational reference only and does not constitute medical advice or product claims.
By purchasing this product, you acknowledge that you are a qualified researcher and agree to use it in full compliance with all applicable laws and regulations.
