Molecular Characteristics
Complete Specifications
Structural Composition
5-Amino-1-methylquinolinium iodide, consisting of a quaternary quinoline ring substituted with an amino group and paired with an iodide counterion
Physical Properties
5-Amino-1MQ is a low-molecular-weight quaternary ammonium compound featuring a positively charged quinolinium core. The permanent cationic charge enhances aqueous solubility and contributes to chemical stability under controlled laboratory conditions. The iodide counterion stabilizes the salt form, while the aromatic ring system provides structural rigidity. Due to its non-peptide nature, the compound is not subject to enzymatic peptide degradation and demonstrates favorable shelf stability when stored in a dry, light-protected environment.
Analysis & Documentation
Identity
Each production lot is checked against the reference structure recorded for this compound:
- Classification — Synthetic small-molecule quinolinium compound
- Molecular formula — C₁₀H₁₁IN₂
- Expected mass — 286.11 Da
- CAS registry — 14047-29-1
- Chain length — Not applicable (non-peptide compound)
- PubChem CID — 122098
Analytical Methods
Testing is carried out per lot by an independent laboratory. The methods measure what the material is and how much of it is the target compound:
- RP-HPLC — reverse-phase separation of the target from process-related impurities; purity is reported as area percent of the main peak
- Mass spectrometry — observed mass compared against the expected molecular mass above
- Retention time — compared against a reference standard run under the same conditions
- Chromatogram — reproduced on the certificate so the peak and any shoulders can be inspected directly
Material & Documentation
What arrives, and how to tie it back to its paperwork:
- Appearance as supplied — Yellow to off-white crystalline or lyophilized powder
- Solubility — Water, DMSO, methanol; soluble in polar organic solvents
- Lot number — printed on the container label and used to look up the certificate
- Certificate — indexed by lot at Certificates of Analysis
Laboratory Handling and Storage Protocols
Lyophilized Powder Storage
- Store at –20°C to –80°C in the original, sealed vial
- Protect from light exposure and moisture
- A desiccated storage environment is recommended
- Stability data suggests extended stability when stored at −20 °C or below.
Reconstituted Solution Storage
- Short-term storage: Up to 7 days at 4°C
- Long-term storage: Store at –20°C in aliquots
- Use single-use aliquots to preserve peptide integrity
- Minimize freeze–thaw cycles; single-use aliquots are strongly recommended
Stability Characteristics
5-Amino-1MQ is a small-molecule research compound with a stable chemical profile under standard laboratory handling conditions. When stored properly and prepared using appropriate solvents, it demonstrates good solubility and resistance to rapid degradation. These properties support reliable use across analytical, biochemical, and cellular research applications when standard laboratory protocols are followed.
Frequently Asked Questions
What is 5-Amino-1MQ?
5-Amino-1MQ is a small-molecule research compound studied for its role as a NNMT (nicotinamide N-methyltransferase) pathway inhibitor in laboratory and preclinical research settings. It is intended strictly for research use only and is not approved for human or veterinary use.
Is 5-Amino-1MQ a peptide?
Despite being commonly grouped with peptides, 5-Amino-1MQ is a small-molecule compound, not a peptide chain. It is often categorized alongside research peptides due to its similar research applications and handling protocols.
How is 5-Amino-1MQ supplied?
5-Amino-1MQ is typically supplied as a lyophilized (freeze-dried) powder or crystalline solid in sealed research vials. This format supports stability during storage and transport prior to laboratory preparation.
How should unreconstituted 5-Amino-1MQ be stored?
Unreconstituted 5-Amino-1MQ should be stored:
-
Long-term: −20 °C or below
-
Short-term: 2–8 °C (refrigerated)
Vials should remain sealed and protected from light, heat, and moisture.
Does 5-Amino-1MQ require a Certificate of Analysis (COA)?
Yes. A Certificate of Analysis (COA) should be available for each batch, verifying identity, purity, and analytical testing results. COAs help ensure transparency and consistency for research use.
Is 5-Amino-1MQ FDA-approved?
No. 5-Amino-1MQ is not FDA-approved as a drug, supplement, or therapeutic product. It is sold strictly as a research compound and must not be marketed for human consumption or medical use.
Can 5-Amino-1MQ be used alongside other compounds in research?
In controlled research settings, 5-Amino-1MQ may be studied independently or alongside other compounds to evaluate pathway interactions or comparative effects. All use should follow proper laboratory protocols and ethical research standards.
Research Background
For a referenced overview of what the published research on this compound examines — and what it does not establish — see What Is 5-Amino-1MQ? Research Background and Study Areas. It cites peer-reviewed sources and contains no dosing guidance.
This product is not for human consumption. It is sold strictly for research and educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.
Any clinical data or research information referenced on this page is derived from peer-reviewed scientific literature and official publications. This information is provided for educational reference only and does not constitute medical advice or product claims.
By purchasing this product, you acknowledge that you are a qualified researcher and agree to use it in full compliance with all applicable laws and regulations.
