5-Amino-1MQ
| Scientific name | 5-Amino-1-methylquinolinium |
|---|---|
| Synonyms | 1-Methylquinolin-5-amine |
| Abbreviation | 5-Amino-1MQ |
| CAS Number | 685079-15-6 |
| Molecular formula | C10H11N2+ |
| Molecular weight | 159.21 g/mol (average) |
| PubChem CID | 950107 |
Mechanisms under investigation
The following are areas of ongoing preclinical investigation. They describe hypotheses and observations reported in the literature, not established clinical effects.
Evidence base (transparent counts)
Selected literature
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Handling and reference
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What is 5-Amino-1MQ?
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Research material & documentation
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Evidence records
- In vitro study in HeLa and HEK-293 cell lines measuring cell viability and selected mRNA and protein levels after exposure to a small-molecule NNMT inhibitor. (2021) — in vitro — PubMed.
- Analytical method study validating an LC-MS/MS assay for 5-amino-1-methylquinolinium in rat plasma and urine samples. (2021) — in vivo — PubMed.
- Medicinal-chemistry study examining structure-activity relationships of small molecule nicotinamide N-methyltransferase inhibitors including quinolinium analogs related to 5-amino-1MQ. (2017) — in vitro — PubMed.
Every record carries a study model, species, support level and review status in the evidence table. Terms used throughout these profiles are defined in the peptide research glossary.
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