Molecular Characteristics
Complete Specifications
Structural Composition
Ala-Gln-Leu-Glu-Arg-Ala-Leu-Glu-Ala-Leu-Gly-Gly-Ala-Gln-Ser-Leu
Physical Properties
ARA-290 is a 16-amino-acid synthetic peptide modeled after the helix-B surface region of erythropoietin. The truncated sequence preserves key structural elements while omitting the full erythropoietin protein framework. Its compact size supports efficient solubility and ease of handling in laboratory environments. Lyophilized formulation enhances stability during storage, while protection from light, moisture, and repeated freeze–thaw cycles helps maintain peptide integrity for research and analytical applications.
Analysis & Documentation
Identity
Each production lot is checked against the reference structure recorded for this compound:
- Classification — Synthetic peptide derived from erythropoietin (EPO helix-B surface peptide)
- Molecular formula — C₄₉H₈₈N₁₆O₂₁
- Expected mass — ~1,257.3 Da
- CAS registry — 1208243-50-8
- Chain length — 16 amino acids
- PubChem CID — Not available
Analytical Methods
Testing is carried out per lot by an independent laboratory. The methods measure what the material is and how much of it is the target compound:
- RP-HPLC — reverse-phase separation of the target from process-related impurities; purity is reported as area percent of the main peak
- Mass spectrometry — observed mass compared against the expected molecular mass above
- Retention time — compared against a reference standard run under the same conditions
- Chromatogram — reproduced on the certificate so the peak and any shoulders can be inspected directly
Material & Documentation
What arrives, and how to tie it back to its paperwork:
- Appearance as supplied — White to off-white lyophilized powder
- Solubility — Water, phosphate-buffered saline (PBS)
- Lot number — printed on the container label and used to look up the certificate
- Certificate — indexed by lot at Certificates of Analysis
Laboratory Handling and Storage Protocols
Lyophilized Powder Storage
- Store at –20°C to –80°C in the original, sealed vial
- Protect from light exposure and moisture
- A desiccated storage environment is recommended
- Stability data suggests extended stability when stored at −20 °C or below.
Reconstituted Solution Storage
- Short-term storage: Up to 7 days at 4°C
- Long-term storage: Store at –20°C in aliquots
- Use single-use aliquots to preserve peptide integrity
- Minimize freeze–thaw cycles; single-use aliquots are strongly recommended
Stability Characteristics
ARA-290 is a synthetic peptide research compound that demonstrates good stability when handled in accordance with standard peptide laboratory protocols. Maintaining proper cold storage, minimizing mechanical agitation during reconstitution, and limiting freeze–thaw exposure help preserve molecular integrity and solubility. When these conditions are met, ARA-290 supports consistent use in in vitro and analytical research applications.
Frequently Asked Questions
What is ARA-290?
ARA-290 is a synthetic EPO-derived peptide designed to selectively activate non-hematopoietic signaling pathways. It is studied in laboratory and preclinical environments to explore tissue protection and cellular repair mechanisms.
Is ARA-290 the same as erythropoietin (EPO)?
No. While ARA-290 is derived from a segment of erythropoietin, it does not stimulate red blood cell production in research models. It is specifically engineered to isolate tissue-protective signaling effects separate from erythropoiesis.
How is ARA-290 supplied?
ARA-290 is typically supplied as a lyophilized (freeze-dried) powder in sealed research vials. Lyophilization enhances stability during storage and shipment prior to laboratory preparation.
How should unreconstituted ARA-290 be stored?
Lyophilized ARA-290 should be stored:
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Long-term: −20 °C to −80 °C
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Short-term: 2–8 °C
Vials should remain sealed and protected from light and moisture.
How should reconstituted ARA-290 be handled and stored?
Once reconstituted:
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Store at 2–8 °C for short-term laboratory use
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For extended storage, aliquot and freeze at −20 °C or below
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Minimize freeze–thaw cycles using single-use aliquots
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Mix gently; avoid vigorous agitation
Does ARA-290 require a Certificate of Analysis (COA)?
Yes. A Certificate of Analysis (COA) should be available for each batch, confirming identity, purity, and analytical testing results to support research quality and traceability.
Is ARA-290 FDA-approved?
No. ARA-290 is not FDA-approved as a drug, supplement, or therapeutic product. It is sold exclusively as a research compound and must not be marketed or used for diagnostic, therapeutic, or consumption purposes.
This product is not for human consumption. It is sold strictly for research and educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.
Any clinical data or research information referenced on this page is derived from peer-reviewed scientific literature and official publications. This information is provided for educational reference only and does not constitute medical advice or product claims.
By purchasing this product, you acknowledge that you are a qualified researcher and agree to use it in full compliance with all applicable laws and regulations.
