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SLU-PP-322

Original price was: $579.99.Current price is: $479.99.

SLU-PP-322 is a small-molecule research compound studied for its activity as a selective estrogen receptor-related receptor (ERR) agonist, particularly ERRα. In research settings, it’s explored for its role in mitochondrial biogenesis, oxidative metabolism, and cellular energy regulation pathways. Intended for research use only, not for human or veterinary use.

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Molecular Characteristics

Complete Specifications

CAS Registry Number: Not assigned (synthetic small-molecule compound)
PubChem CID: Not available
Peptide Classification: Non-peptide small molecule (PPAR pathway modulator)
Molecular Formula: Not publicly disclosed
Molecular Weight: Not publicly disclosed

Structural Composition

Chemical Structure:
Synthetic small-molecule structure designed for modulation of metabolic signaling pathways (exact structure not publicly disclosed)
Length: Not applicable (non-peptide compound)

Physical Properties

Appearance: White to off-white powder (formulation-dependent)
Solubility: Variable; typically soluble in organic solvents and may exhibit limited aqueous solubility depending on formulation

Structural & Stability Notes

SLU-PP-322 is a synthetic small-molecule compound under investigation for its interaction with metabolic regulatory pathways. As a non-peptide compound, it is not subject to proteolytic degradation. Stability characteristics depend on formulation and storage conditions; protection from moisture, light exposure, and elevated temperatures is recommended to maintain compound integrity. Storage in a dry, controlled environment helps preserve analytical consistency for research applications.

Research Applications

Nuclear Receptor Signaling Research

SLU-PP-322 is utilized as a small-molecule agonist in research studies examining estrogen-related receptor (ERR) signaling and transcriptional regulatory pathways associated with cellular energy metabolism. Laboratory investigations focus on its role in:

ERRα/ERRγ Activation Models: Investigation of receptor binding dynamics and transcriptional coactivator recruitment
PGC-1α Interaction Studies: Evaluation of coactivator-mediated gene expression linked to mitochondrial function
Transcriptional Regulation Research: Analysis of nuclear receptor–driven metabolic gene expression programs
Ligand Selectivity Models: Examination of receptor specificity and activation profiles across nuclear receptor subtypes
Compound Stability Studies: Investigation of structural persistence and activity duration in experimental systems

Experimental protocols commonly employ receptor-binding assays, reporter gene systems, and transcriptional profiling techniques to characterize SLU-PP-322–mediated signaling responses.

Mitochondrial Biogenesis and Energy Metabolism Research

SLU-PP-322 has been examined in research contexts involving mitochondrial regulation and cellular energy metabolism pathways. Key areas of investigation include:

Mitochondrial Biogenesis Models: Evaluation of transcriptional pathways associated with organelle replication and function
Oxidative Phosphorylation Studies: Investigation of signaling cascades influencing ATP production efficiency
Fatty Acid Oxidation Research: Analysis of metabolic pathways regulating substrate utilization
AMPK Interaction Models: Research into coordinated signaling between nuclear receptors and energy-sensing pathways
Metabolic Adaptation Studies: Examination of cellular responses to increased energy demand conditions

These studies utilize metabolic flux assays, mitochondrial respiration measurements, and gene expression analyses to evaluate energy-regulatory outcomes.

Skeletal Muscle and Endurance Signaling Research

SLU-PP-322 has also been explored in research models examining skeletal muscle signaling and endurance-associated intracellular pathways, including:

Myocyte Signaling Studies: Evaluation of intracellular cascades associated with muscle energy metabolism
Fiber Type Regulation Models: Investigation of transcriptional pathways influencing oxidative muscle phenotype
Mitochondrial Density Research: Analysis of intracellular mechanisms affecting energy capacity within muscle cells
Lactate Utilization Studies: Examination of metabolic signaling associated with endurance adaptation

Laboratory protocols assess muscle cell markers, transcriptional activity, and intracellular signaling cascades using biochemical and molecular techniques.

Cellular Signaling and Metabolic Network Research

Additional research applications explore SLU-PP-322’s influence on intracellular regulatory systems involved in metabolic coordination and energy homeostasis, including:

MAPK and PI3K-AKT Pathway Studies: Investigation of cascades associated with cellular adaptation and survival signaling
Gene Expression Profiling: Analysis of transcriptional responses linked to metabolic regulatory systems
Receptor Modulation Research: Examination of adaptive signaling modulation within nuclear receptor systems
Integrated Bioenergetic Network Models: Analysis of coordinated signaling systems maintaining cellular energy equilibrium

Research in this domain focuses on understanding how SLU-PP-322 influences nuclear receptor–mediated signaling pathways, mitochondrial regulation, and adaptive metabolic responses under controlled experimental conditions.

Laboratory Handling and Storage Protocols

Lyophilized Powder Storage

Store at –20°C to –80°C in the original, sealed vial
Protect from light exposure and moisture
A desiccated storage environment is recommended
Stability data suggests extended stability when stored at −20 °C or below.

Reconstitution Guidelines

Reconstitute using sterile water, bacteriostatic water (0.9% benzyl alcohol), or an appropriate laboratory buffer
Introduce solvent slowly along the vial wall to minimize foaming
Mix using gentle swirling; avoid vigorous agitation or shaking
Allow complete dissolution prior to use (typically 1–2 minutes)
Ensure the final solution is within a physiologically neutral pH range appropriate for laboratory use

Reconstituted Solution Storage

Short-term storage: Up to 7 days at 4°C
Long-term storage: Store at –20°C in aliquots
Use single-use aliquots to preserve peptide integrity
Minimize freeze–thaw cycles; single-use aliquots are strongly recommended

Stability Characteristics

Selank is a synthetic peptide research compound that demonstrates stable handling characteristics when managed according to standard peptide laboratory protocols. Proper cold storage of the lyophilized material, careful reconstitution, and minimized freeze–thaw exposure help maintain structural integrity and solubility. When handled appropriately, Selank supports consistent use in in vitro and analytical research applications.

Frequently Asked Questions

What is SLU-PP-322?

SLU-PP-322 is a synthetic research compound investigated for its role in metabolic signaling and transcriptional regulation pathways, often in models related to energy balance and cellular metabolism.

What is SLU-PP-322 commonly researched for?

In laboratory and preclinical models, SLU-PP-322 is studied for:

Nuclear receptor pathway investigations
Metabolic regulation and energy utilization research
Skeletal muscle gene expression models
Mitochondrial and oxidative metabolism studies
Transcriptional activation pathway analysis

All applications are exploratory and conducted in controlled research environments.

Is SLU-PP-322 a peptide?

No. SLU-PP-322 is a small-molecule compound, not a peptide, and is structurally distinct from peptide-based research compounds.

How does SLU-PP-322 differ from compounds like AICAR or GW-related compounds?

SLU-PP-322 is studied for its own distinct nuclear receptor and metabolic signaling interactions, whereas other compounds may target different pathways or receptor systems. These differences are evaluated in experimental models.

How is SLU-PP-322 supplied?

SLU-PP-322 is typically supplied as a powder or crystalline compound in sealed containers suitable for laboratory handling and storage.

How should SLU-PP-322 be stored?

SLU-PP-322 should be stored:

At room temperature or 2–8 °C, depending on manufacturer guidance
In a sealed container
Protected from light, heat, and moisture

How should prepared solutions be handled and stored?

Once dissolved:

Store at 2–8 °C for short-term laboratory use
Prepare fresh solutions when possible
Minimize prolonged exposure to light and air
Follow solvent-specific stability guidelines

Does SLU-PP-322 require a Certificate of Analysis (COA)?

Yes. A Certificate of Analysis (COA) should be available for each batch, verifying peptide identity, purity, and analytical testing results to ensure research quality and traceability.

Is SLU-PP-322 FDA-approved?

No. SLU-PP-322 is not FDA-approved as a drug, supplement, or therapeutic product. It is sold exclusively as a research compound and must not be marketed or used for diagnostic, therapeutic, or consumption purposes.

⚠️ Research Use Only

This product is not for human consumption. It is sold strictly for research and educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.

Any clinical data or research information referenced on this page is derived from peer-reviewed scientific literature and official publications. This information is provided for educational reference only and does not constitute medical advice or product claims.

By purchasing this product, you acknowledge that you are a qualified researcher and agree to use it in full compliance with all applicable laws and regulations.

Mg	5 mg x 10 Vials (No labels)

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