For laboratory research use only. Not for human or veterinary use. This is educational reference information, not medical advice.
Hexarelin · Hexarelin (Examorelin)
Hexarelin
Somatotropic Axis Peptides
| Scientific name | Hexarelin (Examorelin) |
|---|---|
| Synonyms | EP-23905; Examorelin |
| Abbreviation | Hexarelin |
| CAS Number | 140703-51-1 |
| Molecular formula | C47H58N12O6 |
| Molecular weight | 887 g/mol (average) |
| PubChem CID | 6918297 |
2D / 3D structure
![2D chemical structure of Hexarelin]()
Mechanisms under investigation
The following are areas of ongoing preclinical investigation. They describe hypotheses and observations reported in the literature, not established clinical effects.
Evidence tiers below reflect how much has been studied in each model type. Counts describe research volume — they do not indicate proven efficacy, safety, or clinical consensus.
Evidence base (transparent counts)
Cellular studies
2 publications
Animal studies
1 publication
Human observational reports
0 publications
Controlled human trials
0 publications
Review articles
2 publications
Selected literature
Filter by study model. Each record is classified for the evidence base above.
2023
Preclinical study examining hexarelin and MDM2/p53 signaling in a model of ischemic acute kidney injury.Animal · mouse · PubMed (37710348)
2015
Review discussing ghrelin and hexarelin in the context of diabetes and diabetes-associated cardiac disease research.Review · PubMed (25645463)
2014
Review summarizing reported cardiovascular actions of hexarelin and its proposed receptor targets.Review · PubMed (25278975)
2004
In vitro study examining hexarelin's effect on angiotensin II-induced apoptosis in cultured rat cardiomyocytes.Cellular · rat · PubMed (14615277)
2001
Cell-culture study reporting the effect of hexarelin on doxorubicin-induced cell death in H9c2 cardiomyocytes.Cellular · PubMed (11322493)
Each record maps to a structured evidence row with study model, species, and support level.
Handling and reference
Molecular weight calculator
Average-mass estimate from a one-letter sequence.
Reconstitution calculator
Laboratory concentration only. Not dosing guidance.
What is Hexarelin?
Hexarelin is a research compound; the identity and structure data shown here are compiled from public chemical databases (primarily PubChem). For laboratory research use only.
What research models has it been studied in?
The literature indexed here is predominantly cellular (in vitro) and animal studies. See the evidence base and publication library above for the transparent counts by study model.
Is there controlled human clinical trial evidence?
Controlled human clinical trials are counted separately in the evidence base above. Cellular and animal findings do not establish human clinical effects.
How is it stored and handled in a laboratory?
Refer to the laboratory information section above.
Is this intended for human use?
No. All information and materials are for laboratory research use only — not for human or veterinary use, and not intended to diagnose, treat, cure, or prevent any disease.
Research material & documentation
This profile is an educational reference. Lot-level laboratory documentation for materials supplied by Peptide Titans is published openly.
Hexarelin research material → · Lot-specific Certificates of Analysis → · How lots are tested →
Evidence records
- Preclinical study examining hexarelin and MDM2/p53 signaling in a model of ischemic acute kidney injury. (2023) — in vivo — PubMed.
- Review discussing ghrelin and hexarelin in the context of diabetes and diabetes-associated cardiac disease research. (2015) — review — PubMed.
- Review summarizing reported cardiovascular actions of hexarelin and its proposed receptor targets. (2014) — review — PubMed.
- In vitro study examining hexarelin's effect on angiotensin II-induced apoptosis in cultured rat cardiomyocytes. (2004) — in vitro — PubMed.
- Cell-culture study reporting the effect of hexarelin on doxorubicin-induced cell death in H9c2 cardiomyocytes. (2001) — in vitro — PubMed.
Every record carries a study model, species, support level and review status in the evidence table.
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For laboratory research use only. Not for human or veterinary use. Educational reference information — not medical advice.