For laboratory research use only. Not for human or veterinary use. This is educational reference information, not medical advice.
IGF-1 LR3 · Long R3 IGF-1
IGF-1 LR3
Somatotropic Axis Peptides
| Scientific name | Long R3 IGF-1 |
|---|---|
| Abbreviation | IGF-1 LR3 |
2D / 3D structure🧬
Mechanisms under investigation
The following are areas of ongoing preclinical investigation. They describe hypotheses and observations reported in the literature, not established clinical effects.
Evidence tiers below reflect how much has been studied in each model type. Counts describe research volume — they do not indicate proven efficacy, safety, or clinical consensus.
Evidence base (transparent counts)
Cellular studies
3 publications
Animal studies
3 publications
Human observational reports
0 publications
Controlled human trials
0 publications
Review articles
0 publications
Selected literature
Filter by study model. Each record is classified for the evidence base above.
2023
Biotechnology study reporting recombinant expression of IGF-1 and LR3 IGF-1 as xylanase fusion proteins in Pichia pastoris.Cellular · PubMed (37261455)
2004
Cell culture study comparing IGF-I and long-R3-IGF-I stimulation of L6 myogenic cell proliferation and differentiation in the presence of recombinant porcine IGFBP-3.Cellular · PubMed (15254966)
1997
Study in neonatal calves examining how nutrition, growth hormone and Long-R3-IGF-I administration altered somatotropic axis hormone concentrations.Animal · cattle (calf) · PubMed (9252489)
1997
Study in pigs reporting reduced growth rate and lowered plasma growth hormone, IGFBP-3 and endogenous IGF-I concentrations following Long [R3] IGF-I administration.Animal · pig · PubMed (9488001)
1996
Protein engineering study designing and characterising long-R3-IGF-I muteins and assessing their resistance to pepsin digestion.Cellular · PubMed (8919033)
1995
Infusion study in guinea pigs reporting increased organ weights alongside reduced circulating IGF-I, IGF-II and IGF binding protein concentrations.Animal · guinea pig · PubMed (7561636)
Each record maps to a structured evidence row with study model, species, and support level.
Handling and reference
Molecular weight calculator
Average-mass estimate from a one-letter sequence.
Reconstitution calculator
Laboratory concentration only. Not dosing guidance.
What is IGF-1 LR3?
IGF-1 LR3 is a research compound; the identity and structure data shown here are compiled from public chemical databases (primarily PubChem). For laboratory research use only.
What research models has it been studied in?
The literature indexed here is predominantly cellular (in vitro) and animal studies. See the evidence base and publication library above for the transparent counts by study model.
Is there controlled human clinical trial evidence?
Controlled human clinical trials are counted separately in the evidence base above. Cellular and animal findings do not establish human clinical effects.
How is it stored and handled in a laboratory?
Refer to the laboratory information section above.
Is this intended for human use?
No. All information and materials are for laboratory research use only — not for human or veterinary use, and not intended to diagnose, treat, cure, or prevent any disease.
Research material & documentation
This profile is an educational reference. Lot-level laboratory documentation for materials supplied by Peptide Titans is published openly.
IGF-1 LR3 research material → · Lot-specific Certificates of Analysis → · How lots are tested →
Evidence records
- Biotechnology study reporting recombinant expression of IGF-1 and LR3 IGF-1 as xylanase fusion proteins in Pichia pastoris. (2023) — in vitro — PubMed.
- Cell culture study comparing IGF-I and long-R3-IGF-I stimulation of L6 myogenic cell proliferation and differentiation in the presence of recombinant porcine IGFBP-3. (2004) — in vitro — PubMed.
- Study in neonatal calves examining how nutrition, growth hormone and Long-R3-IGF-I administration altered somatotropic axis hormone concentrations. (1997) — in vivo — PubMed.
- Study in pigs reporting reduced growth rate and lowered plasma growth hormone, IGFBP-3 and endogenous IGF-I concentrations following Long [R3] IGF-I administration. (1997) — in vivo — PubMed.
- Protein engineering study designing and characterising long-R3-IGF-I muteins and assessing their resistance to pepsin digestion. (1996) — in vitro — PubMed.
- Infusion study in guinea pigs reporting increased organ weights alongside reduced circulating IGF-I, IGF-II and IGF binding protein concentrations. (1995) — in vivo — PubMed.
Every record carries a study model, species, support level and review status in the evidence table.
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For laboratory research use only. Not for human or veterinary use. Educational reference information — not medical advice.