Molecular Characteristics
Complete Specifications
Chemical Properties
Physical Properties
Tesofensine is a phenyltropane-class small molecule that inhibits the reuptake of serotonin, noradrenaline and dopamine. Its monoamine-modulating profile makes it a common subject of neuropharmacology and metabolic research.
Research Applications
Appetite & Energy Balance
Studied for its influence on appetite-regulating pathways:
- Food-intake models — central appetite signaling
- Satiety pathways — hypothalamic regulation
- Body-composition research — preclinical metabolic models
Monoaminergic Signaling
Examined for CNS neurotransmitter modulation:
- Serotonin & dopamine — reuptake inhibition
- Noradrenergic tone — transporter regulation
- Reward pathways — dopaminergic signaling
Metabolic & Energy Expenditure
Investigated in energy-metabolism contexts:
- Energy expenditure — thermogenic and metabolic rate
- Glucose & lipid — metabolic parameter research
Neurological Models
Explored in neurodegenerative research:
- Parkinson’s models — dopaminergic investigation
- Cognitive research — monoamine-linked function
Storage & Handling Guidelines
Capsule Storage
- Store in a cool, dry place at room temperature (15–25°C)
- Keep in the original sealed container, away from light and moisture
- Retain any desiccant packet included in the bottle
- Keep the container tightly closed between uses
Handling Guidelines
- No reconstitution, solvents, or mixing required
- Handle capsules with clean, dry hands
- Do not open, crush, or split the capsules
- Keep away from heat and out of reach of children
Shelf Life & Stability
- Stable at room temperature when stored as directed
- Avoid excessive heat, humidity, and direct sunlight
- Reseal the container promptly after each use
- Use before the labeled expiration date
Tesofensine is a stable small-molecule compound. Store capsules as directed, kept sealed and away from heat, humidity and direct light to preserve integrity for research use.


