Molecular Characteristics
Complete Specifications
Structural Composition
Modified glucagon/GLP-1 hybrid peptide with targeted amino acid substitutions and fatty-acid side-chain conjugation for enhanced structural persistence
Physical Properties
Survodutide is a modified peptide engineered as a dual agonist analog structurally related to GLP-1 and glucagon receptor peptides. Strategic amino acid substitutions and lipidation enhance resistance to enzymatic degradation under research conditions and contribute to extended structural persistence compared to non-lipidated peptides. The presence of a fatty-acid side chain supports reversible binding to circulating proteins, increasing molecular stability. Lyophilized storage and protection from moisture, light exposure, and repeated freeze–thaw cycles help preserve structural integrity and analytical consistency for laboratory applications.
Analysis & Documentation
Identity
Each production lot is checked against the reference structure recorded for this compound:
- Classification — Synthetic dual agonist peptide (GLP-1 / glucagon receptor analog)
- Molecular formula — Variable (lipidated modified peptide)
- Expected mass — ~4,000–4,300 Da (approximate, modification-dependent)
- CAS registry — Not assigned (synthetic modified peptide)
- Chain length — ~39 amino acids (modified, lipidated)
- PubChem CID — Not available
Analytical Methods
Testing is carried out per lot by an independent laboratory. The methods measure what the material is and how much of it is the target compound:
- RP-HPLC — reverse-phase separation of the target from process-related impurities; purity is reported as area percent of the main peak
- Mass spectrometry — observed mass compared against the expected molecular mass above
- Retention time — compared against a reference standard run under the same conditions
- Chromatogram — reproduced on the certificate so the peak and any shoulders can be inspected directly
Material & Documentation
What arrives, and how to tie it back to its paperwork:
- Appearance as supplied — White to off-white lyophilized powder
- Solubility — Water, buffered aqueous solutions (e.g., PBS)
- Lot number — printed on the container label and used to look up the certificate
- Certificate — indexed by lot at Certificates of Analysis
Laboratory Handling and Storage Protocols
Lyophilized Powder Storage
- Store at –20°C to –80°C in the original, sealed vial
- Protect from light exposure and moisture
- A desiccated storage environment is recommended
- Stability data suggests extended stability when stored at −20 °C or below.
Reconstituted Solution Storage
- Short-term storage: Up to 7 days at 4°C
- Long-term storage: Store at –20°C in aliquots
- Use single-use aliquots to preserve peptide integrity
- Minimize freeze–thaw cycles; single-use aliquots are strongly recommended
Stability Characteristics
Survodutide is a synthetic modified peptide research compound designed with extended structural features. Stability depends on proper cold storage of the lyophilized material, protection from light, careful reconstitution, and minimized freeze–thaw exposure. When handled according to standard peptide laboratory protocols, Survodutide maintains structural integrity and solubility suitable for in vitro and analytical research applications.
Frequently Asked Questions
What is Survodutide?
Survodutide is a synthetic peptide analog investigated in experimental environments for its activity at GLP-1 and glucagon receptors, allowing researchers to study dual-pathway metabolic signaling.
How does Survodutide differ from single-receptor GLP-1 agonists?
Unlike compounds that selectively activate only the GLP-1 receptor, Survodutide is studied as a dual agonist, targeting both GLP-1 and glucagon receptors in research models. This allows evaluation of combined receptor pathway dynamics.
Is Survodutide a peptide?
Yes. Survodutide is a peptide-based analog developed for receptor-targeted metabolic pathway research.
How is Survodutide supplied?
Survodutide is typically supplied as a lyophilized (freeze-dried) powder in sealed research vials to maintain stability during storage and shipment.
How should unreconstituted Survodutide be stored?
Lyophilized Survodutide should be stored:
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Long-term: −20 °C to −80 °C
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Short-term: 2–8 °C
Keep vials sealed and protected from light and moisture until use.
How should reconstituted Survodutide be handled and stored?
Once reconstituted:
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Store at 2–8 °C for short-term laboratory use
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For extended storage, aliquot and freeze at −20 °C or below
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Minimize freeze–thaw cycles using single-use aliquots
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Gently swirl to mix; avoid vigorous agitation
Does Survodutide require a Certificate of Analysis (COA)?
Yes. A Certificate of Analysis (COA) should be available for each batch of Survodutide, verifying identity, purity, and analytical testing results to ensure research quality and traceability.
Is Survodutide FDA-approved?
When sold as a research compound, Survodutide is not FDA-approved for diagnostic, therapeutic, or consumption purposes and must be marketed strictly for laboratory research use.
This product is not for human consumption. It is sold strictly for research and educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.
Any clinical data or research information referenced on this page is derived from peer-reviewed scientific literature and official publications. This information is provided for educational reference only and does not constitute medical advice or product claims.
By purchasing this product, you acknowledge that you are a qualified researcher and agree to use it in full compliance with all applicable laws and regulations.
