Formulation & Composition
Blend Overview
Component Profile
Physical Properties
MIC-B12 is a combination research formulation pairing the classic lipotropic factors — methionine, inositol, and choline — with vitamin B12 (cobalamin). The blend supplies these components together in a single vial at the stated concentrations. Lyophilized storage under cold, dry, light-protected conditions is recommended, with minimized freeze–thaw exposure to preserve consistency during analytical use.
Analysis & Documentation
Identity
Each production lot is checked against the reference structure recorded for this compound:
- Classification — Lipotropic (MIC) research blend with Vitamin B12
- Composition — Methionine, Inositol, Choline + Vitamin B12
- Content per vial — 10 mg total blend per vial
Analytical Methods
Testing is carried out per lot by an independent laboratory. The methods measure what the material is and how much of it is the target compound:
- RP-HPLC — reverse-phase separation of the target from process-related impurities; purity is reported as area percent of the main peak
- Mass spectrometry — observed mass compared against the expected composition
- Retention time — compared against a reference standard run under the same conditions
- Chromatogram — reproduced on the certificate so the peak and any shoulders can be inspected directly
Material & Documentation
What arrives, and how to tie it back to its paperwork:
- Appearance as supplied — White to off-white lyophilized powder
- Solubility — Water, buffered aqueous solutions (e.g., PBS)
- Lot number — printed on the container label and used to look up the certificate
- Certificate — indexed by lot at Certificates of Analysis
Laboratory Handling and Storage Protocols
Lyophilized Powder Storage
- Store at –20°C to –80°C in the original, sealed vial
- Protect from light exposure and moisture
- A desiccated storage environment is recommended
- Stability data suggests extended stability when stored at −20 °C or below
Reconstituted Solution Storage
- Short-term storage: Up to 7 days at 4°C
- Long-term storage: Store at –20°C in aliquots
- Use single-use aliquots to preserve integrity
- Minimize freeze–thaw cycles
Stability Characteristics
MIC-B12 demonstrates stable handling characteristics when managed according to standard laboratory protocols for lyophilized research materials. Proper cold storage of the dry blend, careful reconstitution, and minimized freeze–thaw exposure help maintain compositional integrity and solubility. When handled appropriately, the formulation supports consistent use in in vitro and analytical research applications.
Frequently Asked Questions
What is MIC-B12?
MIC-B12 is a research blend combining three lipotropic factors — methionine, inositol, and choline — with vitamin B12 (cobalamin). It is studied in laboratory settings for pathways involving lipid metabolism, methylation, and cellular energy.
What do the components do in research models?
In laboratory investigations, the components are studied for:
- Methionine — methyl-group donation in one-carbon metabolism
- Inositol — intracellular lipid signaling
- Choline — phospholipid and lipoprotein transport
- Vitamin B12 — cofactor activity in methylation and energy pathways
How is MIC-B12 supplied?
It is supplied as a lyophilized (freeze-dried) powder in a sealed research vial to preserve stability during storage and shipment.
How should unreconstituted MIC-B12 be stored?
Long-term: −20 °C to −80 °C. Short-term: 2–8 °C. Keep vials sealed and protected from light and moisture until use.
How should reconstituted MIC-B12 be handled?
- Store at 2–8 °C for short-term laboratory use
- For extended storage, aliquot and freeze at −20 °C or below
- Minimize freeze–thaw cycles using single-use aliquots
Does MIC-B12 include a Certificate of Analysis (COA)?
Yes. A Certificate of Analysis should be available for each batch, documenting composition, purity, and analytical testing results for research traceability.
Is MIC-B12 FDA-approved?
No. MIC-B12 is not FDA-approved as a drug, supplement, or therapeutic product. It is sold exclusively as a research compound and must not be used for diagnostic, therapeutic, or consumption purposes.
This product is not for human consumption. It is sold strictly for research and educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.
Any clinical data or research information referenced on this page is derived from peer-reviewed scientific literature and official publications. This information is provided for educational reference only and does not constitute medical advice or product claims.
By purchasing this product, you acknowledge that you are a qualified researcher and agree to use it in full compliance with all applicable laws and regulations.


