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AOD9604

Name: AOD9604
Brand: Peptide Titans
SKU: 503
Availability: InStock

Price range: $274.99 through $479.99

AOD9604 is a synthetic peptide fragment derived from human growth hormone, studied for its role in lipolysis and fat metabolism. In research settings, it’s explored for its potential to stimulate fat breakdown without significantly affecting growth-related pathways. Intended for research use only, not for human or veterinary use.

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Molecular Characteristics

Complete Specifications

CAS Registry Number: 221231-10-3
PubChem CID: Not available
Peptide Classification: Synthetic peptide fragment of human growth hormone (hGH 176–191)
Molecular Formula: C₇₈H₁₂₃N₂₃O₂₃S
Molecular Weight: ~1,815.1 Da

Structural Composition

Amino Acid Sequence:
Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Ser-Gly-Phe-Gly
Length: 14 amino acids

Physical Properties

Appearance: White to off-white lyophilized powder
Solubility: Water, bacteriostatic water, phosphate-buffered saline (PBS)

Structural & Stability Notes

AOD9604 is a synthetic 14-amino-acid peptide derived from the C-terminal fragment (176–191) of human growth hormone. The truncated sequence is engineered to retain structural characteristics relevant for laboratory investigation while excluding the full-length hormone framework. Its short chain length supports efficient solubility and handling under controlled research conditions. Lyophilized presentation enhances stability, and protection from light, moisture, and repeated freeze–thaw cycles helps preserve peptide integrity during storage and analytical use.

Research Applications

Adipose Metabolism and Lipid Regulation Research

AOD-9604 is utilized as a research compound in studies examining adipose metabolism and lipid regulatory mechanisms. Laboratory investigations focus on its role in:

Lipolysis Signaling Models: Investigation of pathways involved in triglyceride breakdown and fatty acid release
Fat Accumulation Inhibition Studies: Evaluation of mechanisms limiting lipid storage within adipocytes
Adipocyte Metabolic Activity: Analysis of cellular energy utilization and lipid handling processes
Hormone-Sensitive Lipase Pathways: Research into enzymatic systems regulating fat mobilization
Selective Metabolic Signaling: Investigation of targeted signaling activity related to lipid metabolism

Experimental protocols commonly employ adipocyte cell cultures, lipid flux assays, and metabolic profiling techniques to characterize AOD-9604–mediated metabolic effects.

Weight Regulation and Energy Balance Research

AOD-9604 has been examined in research models related to body mass regulation and systemic energy balance. Key areas of investigation include:

Energy Expenditure Models: Evaluation of basal metabolic activity and substrate utilization
Adipose Tissue Reduction Pathways: Investigation of biological mechanisms influencing fat mass changes
Metabolic Efficiency Studies: Analysis of energy conversion and metabolic throughput
Glucose and Lipid Interaction Models: Research into cross-talk between carbohydrate and fat metabolism
Long-Term Metabolic Adaptation: Examination of adaptive responses to sustained metabolic signaling changes

This body of research utilizes metabolic chamber studies, adipose-specific assays, and longitudinal metabolic models to assess systemic responses.

Growth Hormone Fragment Research

As a specific fragment derived from growth hormone, AOD-9604 has been explored in research focused on selective signaling properties, including:

Receptor-Independent Activity Models: Evaluation of signaling pathways distinct from classical growth hormone receptors
Selective Metabolic Signaling: Investigation of targeted metabolic effects without growth-related signaling
Peptide Stability and Activity Studies: Research into structural stability and functional persistence in experimental systems
Signal Specificity Analysis: Examination of pathway selectivity related to metabolic endpoints

Laboratory protocols assess receptor interaction profiles, signaling specificity, and metabolic outcomes using biochemical and cellular assays.

Cellular Signaling and Metabolic Stress Research

Additional research applications explore AOD-9604’s influence on cellular signaling under metabolic demand, including:

cAMP and Lipid Signaling Pathways: Investigation of intracellular signaling involved in fat metabolism
Cellular Energy Stress Responses: Analysis of adaptive mechanisms during altered energy availability
Inflammatory and Stress Marker Studies: Research into secondary signaling responses associated with metabolic modulation
Cellular Homeostasis Maintenance: Examination of regulatory systems preserving metabolic equilibrium

Research in this domain focuses on understanding how AOD-9604 influences lipid metabolism, energy balance signaling, and cellular adaptation under controlled experimental conditions.

Laboratory Handling and Storage Protocols

Lyophilized Powder Storage

Store at –20°C to –80°C in the original, sealed vial
Protect from light exposure and moisture
A desiccated storage environment is recommended
Stability data suggests extended stability when stored at −20 °C or below.

Reconstitution Guidelines

Reconstitute using sterile water, bacteriostatic water (0.9% benzyl alcohol), or an appropriate laboratory buffer
Introduce solvent slowly along the vial wall to minimize foaming
Mix using gentle swirling; avoid vigorous agitation or shaking
Allow complete dissolution prior to use (typically 1–2 minutes)
Ensure the final solution is within a physiologically neutral pH range appropriate for laboratory use

Reconstituted Solution Storage

Short-term storage: Up to 7 days at 4°C
Long-term storage: Store at –20°C in aliquots
Use single-use aliquots to preserve peptide integrity
Minimize freeze–thaw cycles; single-use aliquots are strongly recommended

Stability Characteristics

AOD-9604 is a synthetic peptide fragment that demonstrates good stability when handled according to standard peptide laboratory protocols. Proper cold storage of the lyophilized material, careful reconstitution, and minimized freeze–thaw exposure help maintain molecular integrity and solubility. When these practices are followed, AOD-9604 supports consistent use in in vitro and analytical research applications.

Frequently Asked Questions

What is AOD-9604?

AOD-9604 is a synthetic research peptide consisting of amino acids 177–191 of human growth hormone. It is designed to isolate and study specific metabolic signaling effects associated with this region of the hGH molecule in laboratory and preclinical models.

What is AOD-9604 commonly researched for?

In experimental research environments, AOD-9604 is studied for:

Lipid metabolism and fat-related signaling pathways
Regulation of lipolysis and lipogenesis models
Metabolic and adipocyte signaling research
GH-independent pathway investigation

All studies are preclinical and exploratory in nature.

Is AOD-9604 the same as HGH or HGH-derived peptides?

No. Although AOD-9604 is derived from a fragment of human growth hormone, it does not function as HGH and does not activate the growth hormone receptor in research models. It is studied specifically for GH-independent signaling mechanisms.

How is AOD-9604 supplied?

AOD-9604 is typically supplied as a lyophilized (freeze-dried) powder in sealed research vials. This format supports stability during storage and transport prior to laboratory preparation.

How should unreconstituted AOD-9604 be stored?

Lyophilized AOD-9604 should be stored:

Long-term: −20 °C to −80 °C
Short-term: 2–8 °C

Vials should remain sealed and protected from light and moisture.

How should reconstituted AOD-9604 be handled and stored?

Once reconstituted:

Store at 2–8 °C for short-term laboratory use
For longer-term storage, aliquot and freeze at −20 °C or below
Minimize freeze–thaw cycles using single-use aliquots
Gently swirl to mix; avoid vigorous agitation

Does AOD-9604 require a Certificate of Analysis (COA)?

Yes. A Certificate of Analysis (COA) should be available for each batch, confirming peptide identity, purity, and analytical testing results to support research consistency and quality assurance.

Is AOD-9604 FDA-approved?

No. AOD-9604 is not FDA-approved as a drug, supplement, or therapeutic product. It is sold exclusively as a research compound and must not be marketed or used for diagnostic, therapeutic, or consumption purposes.

⚠️ Research Use Only

This product is not for human consumption. It is sold strictly for research and educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.

Any clinical data or research information referenced on this page is derived from peer-reviewed scientific literature and official publications. This information is provided for educational reference only and does not constitute medical advice or product claims.

By purchasing this product, you acknowledge that you are a qualified researcher and agree to use it in full compliance with all applicable laws and regulations.